I could also kick him in the balls for playing Purple Rain as the FOURTH song in the tribute show in London, no sense of timing.
But yes, it was mainly his ongoing evil Jiminy Cricket act pushing Prince into more extreme religious views (see Kevin Smith talk about Prince putting fans into groups of believers and non-believers) and tactics that affected his health (painkillers vs surgery).
I only witnessed the tribute abberation in-person so certainly could only convict on the basis of that, perhaps a massive wedgie with an option to upgrade to a kick in the balls if he did indeed have a hand in the downward spiral.