*Ahem*, powerhouse of the cell
Jokes aside, this is a terrifying stat: "Although the majority of people infected with the SARS-CoV-2 virus recover within weeks...around one in eight will get long-COVID. Symptoms in patients with long-COVID...include severe cognitive problems (brain fog), fatigue, exercise intolerance, autonomic dysregulation..."
Some covid infections, just like the cold or the flu, cause symptoms longer than the 5-7 days, maybe for 2-3 weeks. That’s long covid. Also remember that long covid symptoms include symptoms like depression and it ends up not being very rigorously defined.
Then there is the version that creates long term chronic fatigue symptoms. That is a much smaller percentage of the population, more like 1% or less. The chances of getting that are extremely small and there’s nothing to be terrified about. You can also get CFS from the flu, and other benign diseases.
Just from looking at the general population it’s easy to see that 1/8 people are not suffering from long covid. Just like how I know someone who got the vaccine and she ended up being crippled by arthritis from the vaccine, but that is not a common side effect at all otherwise we would have seen that more often in the people around us.
That's arguably also terrifying if even common viruses are known to cause long term conditions. Also consider the evidence pointing to a link between viral infection and dementia:
https://www.sciencealert.com/a-study-of-500000-medical-recor...
As OP notes, there are certainly some small fraction people with worse outcomes. But the generic "long covid" term has mixed up all sorts of things -- from hospital syndrome (absolutely real! but very rare!) to symptoms that anyone would completely disregard prior to 2020 as "a head cold" (very common!)
Also, of course, there's a ton of motivated reasoning surrounding this topic where people are in forums and comment threads attributing every symptom under the sun to Covid, and dredging up bad observational studies to support their claims. The link to dementia likely falls in this bucket. It's not coincidental that most of the people to get seriously ill with Covid were/are old, and that most of the people who get dementia are...old.
ME / CFS is a horrible disease. My younger brother was out with it for a year but I know several women for whom it has effectively been a life changing condition.
The article I linked to wasn't about covid.
Observational studies don't/can't perfectly correct for this residual confounding. This exact error has been repeatedly made by "long Covid" research as well (most notably by Ziyad Al-Aly, who has published a half dozen different articles on Long Covid using the same confounded, observational VA medical record dataset, and claimed associations with a huge number of different illnesses. This research is garbage, but it has scared people out of their wits.)
wat.
I lost my sense of smell and taste for ~6 months. Was in bed for 1 week, sleeping like 18 hours per day. Some foods still don't taste the same (mostly eggs and chicken).
This was about 2 days after I got the second dose of Moderna's vaccine.
Base rates and coincidences explain many things better than "vaccine caused my <blah>"
Compared to new-onset arthritis from the vaccine - the biggest lit review I can find found 45 confirmed cases across 31 studies. [1] For comparison there are over 730,000 (self reported, admittedly) cases of long covid lasting more than 104 weeks in the UK alone. [2]
[1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055862/
[2]: https://www.ons.gov.uk/peoplepopulationandcommunity/healthan...
Might be worth looking at https://www.cdc.gov/mmwr/volumes/72/wr/mm7232a3.htm which is more aligned to what this study researched.
(French) https://www.sante.fr/covid-long-2-millions-de-personnes-pres...
1.2% of the French population has long COVID with large/very large impact on daily activities. 4% has long COVID more generally. So I expect more than 1% of chances of getting debilitating symptoms. Though it could be that people with "light" long COVID recover while people with debilitating long COVID don't and make for an unexpectedly high share of the population as they accumulate. (not saying I think that this is the case, just saying this is a possible alternative explanation to "chances of debilitating long COVID are chances of long COVID / 4")
E: changed "we are" to "we might be"
EDIT: I just realised that some people may interpet the comment as saying that long-covid's symptoms are a great thing or something along those lines. I just meant that it would be nice to find such a study. Sorry.
So take the claim with a grain of salt.
https://www150.statcan.gc.ca/n1/pub/75-006-x/2023001/article...
But that study itself notes:
> People that had their first infection early in the pandemic, though, were also more likely to report multiple COVID-19 infections. For example, in this study the average date of first infection for those with three or more infections was May 2021, compared to September 2021 for those with two infections, and May 2022 for those with one infection. Those infected earlier in the pandemic, before vaccination and the emergence of the Omicron variant were more likely to develop long-term symptoms, but also had more time since their first infection to become infected with COVID-19 again.
This is also all self-reported surveys. That means that they're selecting for people who will self-report questionnaires, which is incredibly highly biased.
Immunologically it doesn't make a lot of sense to me and there's no theoretical foundations for how this could be happening. If its linked to people with susceptible genetics/biology (something like MHC subtype) then long COVID should stabilize affecting only that population. If it is due to autoimmunity then people who have formed healthy immune responses to COVID shouldn't increasingly be susceptible after the initial immune response is formed. Give it a few more years, and I strongly suspect that better studies come out finding that long COVID risks decrease over time (although they probably never go to zero, but it starts to look more like flu/cold risk of ME/CFS and that antibodies to vaccination/prior infection are actually protective, like one would logically expect).
Already the progressive subset of my social media is mostly working on the assumption we are seeing a "rapidly rising, ever-worsening reinfections leading to continuously increasing amount of long covid", but that's not what I'm hearing from the medical subset (in person, off the record, not on social media, because they're tired of the whole social media garbage cycle).
There's this Mandela effect in left-leaning circles which thinks that the messaging started with the early 3-month >90% efficacy-against-infection results from Dec 2020, and they're getting fairly hysterical that we abandoned zero covid, when that actually was never the policy. We just collectively all leaped to that hope with the first round of vaccine results because we wanted the pandemic to just have a simple off switch.
And now that's been twisted up into weird us-vs-them political pathologies where the nominally right-wing antivaxxers are shouting about how the vaccines don't work because they weren't what was "promised" while the left-wing is getting hysterical about giving up on covid eradication.
Most virologists/immunologists/microbiologists are happy that we have vaccines that are 95% efficacious against severe disease/death and that the pandemic is either over or winding down (based on entirely debatable definitions), but this pisses off both different political tribes in different ways.
Protection from vaccines has ranged (IIRC) from none to about 50% reduction in probability
Later diagnosed with an autoimmune disorder. Sjogrens. Best I can figure, I had Sjogrens before, but it was so mild. I didn’t really notice or care. After the exposure, all the symptoms were amped up 50 fold. Also had Factor V Leiden. Which went from not an issue to multiple clots every single week.
After about four years, the symptoms dad calmed down to certain degree. Getting Covid was a full relapse for about six months.
Of course my wife got the vaccine and her arm swelled up and years later still hasn’t gone back down.