Italian here, I was trying to access anna's archive today (and libgen as well) without success, is there any easy workaround?
[0] https://support.mozilla.org/en-US/kb/canary-domain-use-appli...
No ISP is going to do nonsense like that for something like copywrite related compliance unless lots of money is forthcoming. An ISP can NXDOMAIN on their own DNS servers at a minimal cost. Doing 53/udp fiddling for all customers means CAM or similar expensive resource usage.
If you do find that your DNS is being redirected as TrueDuality describes, then yes DoH is an option. However if this is an issue then you have far bigger problems than not being able to access Anna's Archive.