Some Mexican pharmacies are selling full bottles of Adderall. But it's meth
latimes.com
latimes.com
At this moment I realized how far we went in wealthy countries, in my case Europe countries, in the regulation of drugs.
They stopped doing it when two things happened.
A) One of their buddies who they lifted with got a counterfeit batch of T and got really sick and spent two weeks in the hospital.
B) Some of the guys at the gym were bragging they were getting T from Mexico too, but would buy it with counterfeit $100 super bills they got somewhere in Vegas (still have no idea how they got them) and then would bring their T back and sell it for a huge profits to other bodybuilders who didn't want to risk getting caught at the border. They eventually did got caught and did several years in a Mexican jail.
Now you just have to go to your doctor and tell him your sex drive is down or you have ED and they'll put on you on TRT pretty quickly without all the fuss. Its pretty standard now for older men to be on a TRT regiment.
I’ve been there and a number of other tourist traps in Mexico, none of it is even close to legit. I would trust a drug dealer on the street over a Mexican pharmacy.
For some reason the community refuses to apply a high of research and rigor to this topic, as if it's lesser than the non-sense we call computer science.
This entire debate is comical, the medical community's approach has been, by it's own admission, to throw various stimulants at ADHD. Methylphenidate, L-Amphetamine, D-Amphetamine, Lisdexamfetamine, etc.
By in large, everyone on this thread is pretending like there is a treasure trove of research demonstrating the superiority of Adderall (a racemic mixture of L & D amphetamine) to Methylamphetamine.
And that's just not true at all, there is a paucity of research on the subject. Meth = Bad because of the Germans and street drug users (who smoke an uncontrolled amount).
I get tired of people that don’t have to deal with ADHD trying to apply some sort of morality to stimulants to treat the condition.
If something else actually worked people would gladly try it. Stimulants have so many downsides and side effects that most would never take it unless it was necessary for them to function. These people are not junkies looking to get high.
Not too surprised to see people say here stuff like “isn’t adderall just meth” dose and delivery methods are completely different.
If your goal was to get inebriated (drinking), would everclear be more effective than vodka?
The Justice Department brought the lawsuit against Purdue Pharma, and distributors are scared.
Have a read here from people who work in the industry https://www.reddit.com/r/medicine/comments/16dur21/stimulant...
I'm sure you didn't mean anything by it, but it's frustrating to hear this line over and over as someone who needs these prescriptions to function.
Meth has higher user ratings on Drugs.com for treating ADHD than dextroamphetamine or Adderall etc have. If it weren’t for the side effect profile and potential for abuse, I reckon it would be the mainline treatment.
I empathize and understand what you mean though. When others say you’re basically on meth, that must not feel good.
B. I've tried meth. It's nothing like Adderall and much, much more potent.
They are the same. The difference is just that the bottle sold as "rubbing alcohol" has been intentionally poisoned.
In the same way that amphetamine is not methamphetamine. Different molecules, different chemistry!
You can get “industrial ethanol” that has some methanol added to prevent people from consuming it, and pay liquor tax on it. These are for chemists for specific applications.
None of these things are “the same”.
I certainly didn't have a scale to measure the dosage to match say a 10mg orange adderall pill.
By analogy, if you did a 75ml "shot" of alcohol each day, and then had a mixed drink one day, you would think it's a lot more potent.
For a given quantity, eg 1mg, of methylamphetamine vs d-amphetamine, the meth will release more serotonin?
I remember thinking "Why would anyone want to feel like this?" Will never touch the stuff again.
I just weighed a couple 20mg orange adderall pills, they're each around 0.2-0.3 grams (my scale is only accurate to 0.1g)
A lot of people that have tried both meth and amphetamine in comparable dosages would tell you they are very comparable, though.
I'd add that the people I've known who did a lot of meth tended to have physical health issues and looked like shit, which was not the case with the people I've know who abused Adderall.
Method of administration affects the time delay for euphoria. Smoke > Shooting > Eating.
People who do a lot of meth (or drugs outside of a prescription) tend to do as much as they can purchase and/or tolerate.
When you see someone who has a doctor (dealer) that gives them as much adderall as they want, illusions of differences between the two drugs rapidly fade. I'm talking about 100+mg a day, I've seen it happen, still have 50mg adderall pills from the person in the story.
The methyl group attached to the amine basically just helps it cross the blood brain barrier better and makes it more resistant to enzymatic destruction. This means it is a couple times more potent dose-per-dose and lasts longer. It's nothing like the difference between methanol and ethanol, where one will kill you and the other is fine to drink. That IMO a rationalization people with ADHD make to convince themselves their prescribed amphetamines are somehow qualitatively different than big scary meth--just like the rationalization that amphetamine acts magically different in people with ADHD (it calms everyone down in low doses, it just might not provide the same working-memory deficit correcting effects as there is no deficit). In fact, in most of Europe, amphetamine itself is what you find on the streets, not meth.
Adderall is normally prescribed in the XR formulation (meaning it's an extended/slow release capsule), and has amphetamine as the active ingredient.
Methamphetamine is a different molecule altogether, and typically it's not packaged in slow-release capsules.
Yes, methamphetamine is structurally related to amphetamine, but you shouldn't make the mistake to think they are interchangeable. Very often the difference between two very similar molecules is the difference between life and death (for a classic example, look up the two enantiomers of thalidomide).
If we just discussed this as d-amphetamine, l-amphetamine & methyl-amphetamine, the issue of interchangeability would be less confusing.
Talking about methamphetamine as a different molecule is not helpful, as Adderall itself is not a single molecule.
Which I suspect you know, as you mention different enantiomers of thalidomide. However you don't point out that adderall itself is a 3:1 racemic mixture of l and d amphetamine.
The real discussion here is the receptor binding affinity of the various targets of the drugs, and how they compare.
The vast majority of adderall prescriptions are XR.
Enantiomers are structurally “the same molecule” (or people often speak this way depending on the context) but with different optical configurations.
There's a whole section, "Single-Isomer Versus Racemic Formulation", in this recent review article titled "Novel Formulations of ADHD Medications: Stimulant Selection and Management" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412159/
The psychiatry handbook of Massachusetts General Hospital also uses racemic in this context https://www.sciencedirect.com/science/article/abs/pii/B97814...
Also, I can't find any data on what percentage of Adderall prescriptions are XR, have you found anything?
Looks like the LRx database would be the place to look from scanning this report for the DEA. https://www.deadiversion.usdoj.gov/pubs/docs/IQVIA_Report_on...
Meth is apparently prescription meth.
Section 3 of this 2019 paper has stats on meth (desoxyn) prescriptions https://www.medrxiv.org/content/10.1101/2022.05.23.22275471v...
I mean, there's that.
Look, this is what I'm driving at, you appear to have some illusions that methamphetamine is significantly different than other amphetamines, or has some higher toxicity profile, more addictive, IDK I'm trying to get you to tell me your biases.
At that point, we can go look at the clinical literature and see what the evidence is.
Note that you've gone from this statement, to acknowledging that they are regularly prescribed.
> Imagining a doctor writing a script for meth is pretty amusing, and maybe if that’s not a cool enough drug, they can hand out some crack or something.
The 4000:1 prescription number would seem to corroborate my impression that it is quite rare.
As with meth, typical medical applications of cocaine don't involve smoking it (source: Wikipedia).
Legitimate US suppliers for smokable cocaine do exist, however, e.g.,
https://www.sigmaaldrich.com/US/en/product/sigma/c8912
In stock and available for shipping today* **!
* “This order may require review prior to shipping.”
** “DEA License Number required at checkout.”