Off the top of my head, https://pubmed.ncbi.nlm.nih.gov/19230461 from 2009 but there are many earlier studies as I recall.
Off the top of my head, https://pubmed.ncbi.nlm.nih.gov/19230461 from 2009 but there are many earlier studies as I recall.
The only problem is that the pharmacy always seems to be closed when you need it.
IME, guafenesin can be helpful for making coughs more productive, hydration helps with that too, and again IME, so do spicy foods. Mixing cough suppresants and expectorants together makes no sense, but is common --- if I'm trying to clear the junk in my lungs with an expectorant, why am I supressing the coughs that are needed?
Because you need sleep too. And if a cough isn’t productive, having more of them doesn’t help, it only hurts.
The ideal case is to have a minimal number of coughs that are productive.
For suppression of 'ticklish' coughing (i.e. where any form of very minor irritant in the air will set off a coughing fit): Dextromethorphan, which is an antitussive (and which is psychoactive and depending on genetics WILL make you trip even at therapeutic non-abuse doses)
For 'sticky' coughs where the mucus refuses to depart: Ambroxol, which functions as a Mucolytic, i.e. it makes the mucus/phlegm thinner by causing partial breakdown of them, i.e. it fucks with phlegm composition which in turn fucks with the phlegm's rheological parameters
For 'dry' coughs, where there isn't enough mucus: Guaifenesin, which functions as an expectorant (albeit as explained below, "Secretolytic" seems like the better term by far), ramping up mucus production/bronchial secretions/hydration. (avoid confabulating with Guanfacine.)
And then of course for ticklish coughs/antitussive action, there's two other, much better solutions, but ones with it's own issues: Codeine & Dihydrocodeine. Works wonders — as long as your CYP2D6 doesn't function in an atypical manner, in which case it'll either not work at all or get you way too high.
Part of the problem is that a lot of the literature uses the word "expectorant" in the same way I used it above, but really, the more appropriate word to describe guaifenesin is "Secretolytic".
Obligatory disclaimer:
this comment isn't medical advice, I'm neither a medical professional nor a medical paraprofessional, in case of concerns, contact/consult an appropriate medical professional and/or appropriate medical paraprofessional.
I wish I knew why no combination of Guaifenesin & Ambroxol seems to exist on the market, but there probably exists SOME reason.
To any professionals reading this:
Sorry for the low quality content, I know it's very flawed
As someone who suffered chronic congestion, and had experienced the effectiveness of pseudoephederine, it was immediately obvious that phenylephrine did nothing. It's just surprising that this "open secret" has taken 20+ years to be publicly confronted.
But it's not homeopathic -- the defining property of "homeopathic" remedies is that they have been progressively diluted until they consist of only pure water.
The second part, why they are getting away with it, is that naturalistic and pseudoscientific healing BS has a long, long history in Germany. Schulmedizin, at least somewhat, had the image of being perverted by Jewish influences. "Völkische Medizin" the OG Heilpraktiker in some sense, started most of the Quack stuff you see today. The same circles are also still infested with nationalist and anti-jewish sentiments á la "the globalists" to this very day. It’s a crazy, crazy world if you take a closer look.