16GB is not enough.
32GB is enough to run quantized Mixtral, which is the current best openly licensed model.
... but who knows what will emerge in the next 12 months?
I have 64GB and I'm regretting not shelling out for more.
Frustratingly you still have WAY more options for running interesting models on a Linux or Windows NVIDIA device, but I like Mac for a bunch of other reasons.