There is no place to hide anymore (nowadays).
A single hit? Probably.
But now imagine a series of bunker-busting MIRVs from a single ICBM arriving in sequence behind each other. Each one carving out a nice crater, for the next one to go even deeper.
A thermo-nuclear jackhammer.
With that jackhammering a few hundred kilotons per MIRV/hit would be sufficient, I guess. More would be wasted. Goes just up in the air.
Each ICBM carrying anything from a hand full, to a dozen(maybe even 20?) of such MIRVs.
Now, how many ICBMs would be needed? 2? 3? 5? 10?
Let's try! BAM-BAM-BAM-BAM-BAM-BAM-BAM-BAM-BAM-BAM... Yeee Haa!
That aside, this location has 2400m of mountain over it, but the access-ways are probably on the sides, way lower, not necessarily in some steep gorges.
Probably simpler to use them as starting point for the 'jackhammer', if only for the shockwaves of hot plasma to propagate more easily into the deeper structures along them, and wreaking havoc.