1. No wireless charging. Switching to this phone would require a big change in my household's ecosystem (sorry to use a big word for a small thing, but I can't think of a better one). We have $10 wireless charging discs all over the place, and it's nice to be able to charge whenever we set our phones down. I don't want to take a step backward.
2. The Verge's review suggests the camera is OK but not great. I've been taking Pixel photos for years, and my phone is always the one people ask to use for group shots at social events. I don't want to fuss with taking a picture ten times just to get the lighting right, and the Pixel almost always meets the bar on the first shot. It sucks that a consumption device like a phone has this one critical input feature, and that there is still so much of a computational photography gap between certain brands and the rest, but that's how it is, and it prevents me from seriously considering any of them. (This isn't unique to Pixel; I hear Apple does well in this area, too.)
3. Just a nit: why is the case 40 euros? I expect to pay a premium for the phone because of the specific compromises in the design and the resulting low volumes. But this is just another run-of-the-mill TPU case that I expect I'd have to routinely replace every couple years. I don't use screen protectors, but I have an even more allergic reaction to the 33-euro price of the one for sale. I know there are aftermarket options, but I'm already taking a risk of poor part/accessory availability in the future because it's a niche product, so I don't know whether they'll still be available when I need them years from now.
By the way, I do own a Framework laptop (11th-gen CPU), and I like it a lot. I plan to swap out the motherboard next year. Unlike the Fairphone, the Framework didn't impose cost and performance compromises right out of the gate. I support sustainability, but there's only so far I'm willing to go.