People keep thinking in terms of Drake's equation, and I for one am puzzled. Don't people realize that under any imaginable and non-imaginable scenarios, life outside our galaxy is irrelevant for us? There's no way we can exchange a single "Hello" with a neighbor in Andromeda, and that's the closest galaxy out there.

I don't personally deny that there could be life in other galaxies, but equally, there could be angels dancing on the tip of a hairpin. Maybe there are, but neither can affect my life in any way.