With uBlock Origin working as it works best on Firefox, I get a 3-5 sec lag on launch [0] as it prepares the browser to block ads.
With Chrome, the launch happens in an instant. I should also mention that Firefox has always had a slow start up time on my machine.
While am sure there is a setting to turn the uBlock feature off, it probably won't make enough of a difference to beat Chrome's start up time.
[0] https://github.com/gorhill/uBlock/wiki/uBlock-Origin-works-b...