• Most importantly, it makes fallback and load-balancing available for regular people; just spin up an extra web server somewhere else and add it to the DNS, just like a secondary MX. Mostly no need for a CDN anymore.
• The importance of SNI is lessened, since the DNS can now point to a port number as well as a host name. This makes it possible to have web server configurations without an enumeration of all server names; just have the web server use a certificate from a file and listen to the correct port number – no need to configure host names.
• The possibility to have separate web sites use different ports makes process isolation easier without having to go through a gateway host.
• It frees the apex DNS domain name from having to have an IP address; an IP address is harder to keep updated than a simple host name of a web server.
In summary, these things either make it easier to live on today’s internet without Google, Cloudflare, or other centralizing actors, or they make it easier for the smaller web hosting providers, or both.