I don't do graphic design any more, but I started with GIMP - when I was first able to try Photoshop (pre GIMP redesign) it was awful, nothing made sense, nothing was where it should be. In contrast, when I first used Corel Draw it seemed intuitive.
Just like using a Mac after having been a PC user; or being forced back to MS Windows after using Linux/KDE for a couple of decades.
I used to use Inkscape heavily, but having not used it for a few years, I go back and the UI has changed, similar experience; I feel lost when I should feel capable.
Photoshop was one of the first applications that I noticed using the 'give it free to college students to capture the market' technique. That works so well because it takes a couple of years for for you to adopt the software as an extension of your way of thinking - changing application means a productivity loss, and a feeling of incompetence, and no professional wants that unless they can clearly see an ultimate gain.