C2PA is more about tracking origin and edit lineage for e.g. press photographers. It does not determine if an image is a deepfake or not. Create a deepfake then take a picture of it with a C2PA camera, now you've got a C2PA-stamped deepfake.
But supposed you take a C2PA photo and then edit its contents with e.g. generative in-fill. The updated C2PA stamp from that action will get noted and can be audited later on.