In my opinion, there isn't really a palpable benefit to be gained from totally re-engineering GUI event handling. Processes that are so CPU intensive they cause the GUI to lag are uncommon (and easily dealt with when they do occur). Even if a re-engineering of the GUI event architecture did occur, that would be a systems level issue, and most developers could remain oblivious.

I like Clojure, I think Rich did a great job with the data structures. My only gripe is that it would be a lot more elegant if the notion of transients went away completely. I think transactions with automatic commit and branching on reference creation would be much nicer (and faster). Still a very well engineered language by and large.