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So many foundational bioinformatics tools are broken and I just want to rewrite them all.

Interested in this as well - do you already work on this somewhere out in the open?

which ones are you thinking go?

I'm interested in this space too-- it'd be great to get in touch and discuss (my contact info in my profile).

same, i've been trying to do proactive / productive work in this field

I think I'd do anything with a friendly team

Interested as well! But the future is not so dark, things like e.g. https://github.com/lh3/minimap2 are a breath of fresh air.

Heng Li is an outstanding contributor to bioinformatics.