I've played around with it a few times, since it's been easily available in NixOS for a while. Didn't run into any issues with a few disks and a few hundred GB of data.
Some very interesting properties, including (actually efficient) snapshots, spreading data over multiple disks, using a fast SSD as a cache layer for HDDs, built-in encryption (not audited yet though!), automatic deduplication, compression, ...
A lot of that is already available through other file systems (btfs, zfs) and/or by layering different solutions (LVM, dm-crypt, ...) , but getting all of it out of the box with a single FS that's in the mainline kernel is quite appealing.