For non-believers, though, earthly life is all there is, so reducing suffering, disease, and poverty are much more pressing goals -- goals that might be worth a little alienation.
I would emphasize choice: people can (and do) embrace alternative ways of life, from the Amish to kibbutzim. Similarly, we don't have to drag out our final years: we're free to opt out of medical treatments. You can also opt out of modernity in smaller ways, decisions like not owning a car, not watching TV, and so on.