I would pick what I'm most comfortable with, a simple monolithic Nest.js application running Fastify, with Postgres or SQLite, Dockerized, hosted on a predictably-priced host like Hetzner, and Ansible to automate everything. I know that stack will give me plenty of headroom until I eventually need to scale differently.
Front-end is still React, which has a massive ecosystem, and I feel like I can do _anything_ with it by just bringing in some dependencies, if it's a passion project then I want to deliver features fast, React allows me that.
I feel like a dinosaur, edge, workers, cloud functions... I'm familiar with none of that magic, there's probably a whole universe of amazing new ways to build for the web I'm sleeping on, but at that point I don't even care really.