50% was on the low end, 10 years ago when I submitted my first proposal. I’ve been out of the game for a while now, but I don’t think the rates have gone down.
In my experience, when universities are allowed to submit straightforward total cost bids for things like contracts, we're often fairly competitive with private industry.
Here is old news that the HN community needs to catch up on.
https://www.science.org/content/article/nih-plan-reduce-over...