Where are these magical lands? I've lived in Atlanta and the SF Bay Area, and the salary difference between the two for engineers is around 30%, although house prices aren't much cheaper in the former - unless you want to live in the suburbs, and then you make up the difference in gas.
Medical specialists are tied to hospitals, some of which may be more affordable areas, but technologists (who this site arguably caters to) tend to be bound to tech hotspots, where house prices near $1MM don't raise eyebrows.