It's exactly the same latency that a request to an API will have.
Obviously Livewire is not a good option for interactivity that happens exclusively in the client.
Every interaction in a livewire type system requires a round trip - that's not true for SPAs. Let's say I'm developing a node based editing UI with drag and drop that lets me connect things. How on earth are you going to make that work with livewire?
You’re wrong on this. You’d use Alpine and do the interactivity client side. If you don’t miss use the tool, Livewire is supposed to reach to the server in the same situations an SPA would reach to the server (updating or refreshing server state)