There have been a ton of articles and studies that show fecal transplants (FMT) from a healthy donor are one of the most effective ways to cure an overgrowth of c-diff. I couldn't get a doctors appointment at a specialist for weeks and was desperate so read the studies and methodologies in detail and did it myself. The key is finding a healthy donor. I decided my 8 you son would be perfect as he is super healthy and generally has the same diet as I do. I won't go into all the details but suffice to say the basics involves a mixer, sample, and enema which you then retain for as long as possible (2+ hours ideally).
It was the single most transformative medical treatment I have ever tried. Within a day or two symptoms were down I'd say 80% and within a week I was 100% better (which was confirmed a few weeks later when I finally got an appointment for blood testing and colonoscopy) Not only that I actually felt better than I had in years; consistent brain fog and ADHD symptoms alleviated as did some of my allergies. I was absolutely blown away.
I strongly believe this will eventually be viewed as a go to treatment for all kinds of neurological and other pathological diseases. I could imagine donor samples being further refined to increase or decrease specific micro-organisms contained to better target specific illnesses. There are several companies that have developed fecal transplants that are conducted via pill form in which the outside is sterilized in order to get rid of the ick factor.
>"It's entirely possible gut microbiome is a causative factor (even partial) in the obesity epidemic too. Everyone is obsessed with the CICO idea, but humans are not a blast calorimeter and the actual absorption, satiation, or metabolic paths all have obvious links to the gut microbiome (much more intuitive than the links to neurotransmitters)."
Absolutely. In fact as I was researching fecal transplants I came across a couple of interesting medical case studies in which obesity from the donor was passed to the recipient (which also underscores the importance of donor screening) [1]