It's quite an interesting architecture. From an initial perusal, I found these features note-worthy:
* Explicit access to PC as a register, makes "computed goto" trivial and very natural.
* Because of the above, there is no JMP instruction.
* Treating operations on registers as "values" makes the instruction set very orthogonal.
* No instructions for bit-manipulation.
* Lots of possible NOP instructions, like "SET PC,PC" (which I think should work, depends a bit on exactly when it's incremented but it looks safe).
* Word-addressed memory will make string processing interesting to implement. Maybe in space, everyone uses UTF-16.
* Single 64 K address space will put quite the limit on the amount of code, I guess the game will show how much code is needed to do anything.
* No I/O instructions means I/O must be memory-mapped, further reducing the space available for code. Maybe there will be bank-switching?
* No interrupts.