R also seems to have some libraries for things related to design of experiments.
JMP is also a very criminally underrated and flexible tool to do data analysis with – both exploratory and modelling. It's my preferred tool of choice over R, especially after they added a structural equation modelling platform.
It's a pity they got rid of pricy perpetual licensing quite a few years ago for a no less pricy subscription model.
For biology, Synthace supports designing experimental protocols using DOE, executing them on robotically automated lab equipment, then performing analysis on the results: https://www.synthace.com/