Half of the side effects are also the side effects of abating depressions.

It's theorized that the suicide risk from most anti-depressants are from transitioning from so depressed that you have no motivation to do anything, to having enough motivation, but still feeling the related pain from depression.

Likewise with weight-gain. For many depressed people they have a suppression of appetite, and relieving the depression causes return of appetite.

AFAIK, neither the sexual side effects nor the withdraw symptoms are generally considered to be long term much less permanent.