Yep. Imagine doing multiplication in Roman numerals :)
https://huggingface.co/spaces/Xenova/the-tokenizer-playgroun...
https://cacm.acm.org/blogs/blog-cacm/234881-how-did-the-roma...
The main advantage of Arabic numerals on paper have is that operations are non destructive and you can restarts a calculation if you lose your place. The main disadvantage is memorising the times table and the amount of scratch paper you need.