Arguably only Lisp Machines hold that distinction. The other common targets are C, LLVM,Arm and x86. I don't see how they can be said to be designed any more specifically for lisp. At least the LLVM and CLR have TCO.
At least x86 was never written for one particular language.
The processor had some new instructions (not present in the 8080 and 8085) to better support stack based high level programming languages such as Pascal and PL/M; some of the more useful ones were push mem-op, and ret size, supporting the "pascal calling convention" directly. http://en.wikipedia.org/wiki/Intel_8086