Hacker News Reader

T1 kills you with 50% chance in 2 years, without insulin. With hypertension, you can leave 10+ years. Not nearly comparable.

View on HN

Wait. You can survive with T1 for two years without insulin, 50% chance? Your pancreas must be still working, but when it totally stops producing insulin, I'd give you maybe a week before going to a coma.

If I unplug my insulin pump, I will feel very sick after 24 hours and probably go to a coma from ketoacidosis after a few days.

That's data from early 20th century, so take it with some grain of salt. Nobody would redo proper double-blinded trials nowdays :) Maybe it was measured from the onset, when you still had some b-cells active? Furthermore, people live with 20-30 mmol/L, so it might be not a week even with zero production - our body's adaptability is huge.

Is there a threshold you're using for non-intervention mortality and why did you choose it as the only factor?

Additionally, most people would seem to account for several inputs, HR for all-cause mortality seems like a pretty good indication, but you've chosen to reject it. Any reason?

Reply on news.ycombinator.com