The difference is that statistics were used in de Berk's prosecution, but were not used in Letby's prosecution.
Though unlike the Lucia de B case it doesn't seem likely these deaths could all have been natural. The evidence pointing towards Letby seems mostly probalistic in nature though, which should be treated carefully.
Chief among these was the duty roster spreadsheet showing staff shifts, through which the Crown Prosecution Service (CPS) was "able to show the jury that Letby was the one common denominator in the series of deaths and sudden collapses on the neonatal unit".
https://theweek.com/law/lucy-letby-and-the-importance-of-und...
That is totally statistical information - even though it's, shall we say, lay statistics and not what you'd expect to see from a statistician.