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Comment by robinduckett | Hacker News Reader

Anecdotal: I have been on Liraglutide and Semaglutide and it has helped considerably with weight loss, but does have side effects that aren’t great but has not yet hit me with suicidal thoughts.

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Would you describe the side effects you have experienced?

If you eat any heavy food, you get diarrhea/vomiting. I once ate a curry while on semaglutide and I spent the whole night on the toilet, but the worst was the burps. The diarrhea cleared up by morning, but I had these disgusting, revolting burps from the food basically rotting in my stomach. They stank up the whole room and smelled like decomposition.

Semaglutide doesn't make it so you don't want to eat, it makes it so you regret doing it. I quit it shortly after, since I only have a few extra kilos I want to lose (so it wasn't worth it), and because I didn't want to lose the weight by being punished for eating. I figure that if I'm going to have a list of foods I absolutely must avoid, why do I need the semaglutide?

Wonder if drinking something like Yakult while eating the heavy meal would work?

https://en.wikipedia.org/wiki/Yakult

Am kind of thinking that the "rotting in your stomach" would be countered by the probiotic bacteria doing their thing.

My partner experienced the burps thing, but not so much me - I get a little bloating and weird poops.

I definitely agree it makes you regret over eating, but I also find it makes you not want to eat. Just enough of an edge to make weight loss a breeze

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