This seems highly debatable. Sure cheap calories and cheap corn based sugars make it easy to develop so called lifestyle diseases, but on the other hand we've essentially eliminated famine and in most parts of the world malnutrition.
In terms of ecosystem loss, it seems to me that concentrating most calorie production onto the smallest amount of land makes sense.
> And the labor issue is also complex
You're right of course, but I don't see how the manually intense process of regenerative and/or organic ag makes this better. Every small farm like this that I'm aware of makes heavy use of children, unpaid interns, and extremely low wage workers. It's not exactly comparable to migrant workers picking strawberries en-masse, but that's more of an issue of sacle and where these boutique farms find their labor IMO. I say this as someone whose parents and grandparents were all farmers, and my sister-in-law worked for a few years on a regenerative/organic farm.
> But a lot of the ideas from more fringe communities like permaculturists are becoming more and more integrated into the mainstream
This is the part that's actually really interesting to me. Finding ways to scale up and integrate ideas about soil health, water use, etc into mechanized, large scale agriculture is really great. People seem to be doing cool things with no-till and drip irrigation right now.
> alternative methods like agroforestry
My concern with this is that it definitely require LOADS of labor, and isn't likely to produce that much food. It also may put pressure on forest land may not be sustainable long term. On a small scale on you your own farm, it's probably great. But I have trouble imagining how it could ever make up a significant portion of overall fruit and nut consumption.