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vim-slime apparently also works with tmux, which has a much more understandable documentation in my experience. Might be worth taking a look?

tmux is something that I've been meaning to take a look at. It's hard once something gets muscle-memoried in though, you know what I mean?

tmux keys all remap pretty nicely. The recent tmux book to come out is pretty decent as an intro primer to tmux, getting you going pretty quick

Is this the book?

I believe there's even a "screen-compatible" default config file that ships with tmux.