I would definitely want to see async totally overhauled. Also it would be great if major components of the standard library were all version 1.
And if I want to risk going too far, I'd also advocate for refactoring the type system to be slightly less generic in favor of chasing faster compile times.
Also, ideally the lead designer of SafeLang2.0 would be much more heavy on engineering experience than PL theory. Rust made a lot of tradeoffs that were beautiful in PL theory but are annoying to use on a day to day basis.
I honestly think rust is equal parts amazing ideas and mediocre ideas, and I think a slighky less ambitious language would still be almost as safe (world class compared to any other language) but 10x more fun to use.