Conservator 'best practice ' changes pretty much every decade, with each generation of conservators dismayed at all the damage done by their predecessors...
The other important property is that these materials are often designed to show up visibly under UV light. That way they can perfectly blend in the base paint under normal gallery lights (if desired, this is not always desired) but they will always show up for someone who investigates the painting in the future.
1: All my knowledge about the topic comes from the aforementioned Baumgartner Restoration YouTube channel: https://www.youtube.com/c/BaumgartnerRestoration