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Comment by jacobsimon | Hacker News Reader

I just came here to say that I actually find phenylephrine nasal spray quite effective - but I use it for a different use case: stopping nosebleeds quickly. It's quite effective at that and came recommended by an ENT, so I do believe it's an effective vasoconstrictor when applied locally and I'm glad it's available.

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That's legitimate. The FDA's issue with oral phenylephrine is that it's metabolized in the gut before it gets to the sites where you want it to work.

I wonder if it will work as a suppository.

It’s worth a try. I’d recommend buying a separate spray for your nose though.

“This medicine smells like crap.”

Reminds me of the old joke: what's the difference between an oral thermometer and a rectal thermometer?

Answer: the taste

"Oh, Dad..."

Seriously, my late father _loved_ that joke, as do I.

I heard that for the first time from my dad. It's a certified dad joke.

As a certified dad, I have to agree.

This reminds me of the funniest scene in the movie Idiocracy, where he loses track of which cable goes in the mouth vs ear vs butt. A laugh a day keeps the doctor away, enjoy :-)

https://youtu.be/zop3VG_K9HU?si=k8LDptGhvQDxtsTB

For the future, please remove the ?si= parameter from your YouTube share links. It uniquely identifies you and allows Google to track your social circle with certainty. (Not that they couldn't do it already)

what if he wants google to know his love for idiocracy?

Yup!

https://my.clevelandclinic.org/health/drugs/20786-phenylephr...

Phenylephrine is a popular topical and suppository treatment for hemorrhoids.

This. Phenylephrine works great as a decongestant nasal spray, and it's not as addictive as oxymetazoline. (It doesn't last as long either, but that doesn't bother me.)

I wonder if it could be applied to the under-eye area to reduce dark circles caused by thin skin. People use caffeine topically for this reason.

EDIT: Looks like it does work for this! Nice!

As per the article, you would likely be correct

You are correct.

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