Set & Setting, dosage is important.
https://pubmed.ncbi.nlm.nih.gov/25586396/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286320/
Personally for me, it helped me quit alcohol, cannabis, and even alleviated my diagnosed ADHD permanently so I quit taking my prescribed stimulant medications. I used it in a therapeutic environment, not with friends or at a party.
After numerous Ayahuasca ceremonies, turns out my traumas/upbringing led to the addictions in the first place.