Turns out the ping testing device was last configured with the IP of a critical application server that talks to every device in the plant. When the colleague pressed the button, every plant device stopped contacting the apps server and the plant went down. Unplugging the device eventually fixed it. The line was stopped for 7 minutes. I believe stoppages were usually quoted at tens of thousands of dollars per minute and billed to the responsible department.
I remember how stressed everyone was after and meetings for root cause analysis in the following days. I was always surprised at this considering how frequently the line went down for small amounts of time, and they never seemed as big of a deal as that one specific time, though for the others we were not responsible.