A little over 2,000 years ago someone wrote Elihu's speech in
Job where he claimed God was unknowable because why it rained or where snow came from was beyond human understanding, so how could we understand something like God.
Claims of what can't be known often tend to turn out to be wrong.
Even in terms of discussion of understanding our own universe this may be the case.
A century ago physicists had their minds blown by the discovery of quantum mechanics on the tail end of having just discovered general relativity.
Still today, physicists struggle in unifying those two models, with the former discrete and the latter continuous.
Meanwhile in just the past few decades, we've landed on a similar paradigm for a very niche application. This is from Nvidia's GPU Gems book chapter 39:
Although the data set is interpreted as a continuous function in space, for practical purposes it is represented by a uniform 3D array of samples. In graphics memory, volume data is stored as a stack of 2D texture slices or as a single 3D texture object. The term voxel denotes an individual "volume element," similar to the terms pixel for "picture element" and texel for "texture element." Each voxel corresponds to a location in data space and has one or more data values associated with it. Values at intermediate locations are obtained by interpolating data at neighboring volume elements. This process is known as reconstruction and plays an important role in volume rendering and processing applications.
We are in what appears to be a continuous universe at macro scales which at low levels of fidelity behaves as discrete probabilities which alter based on interactions and observation.
Meanwhile we're building virtual environments functionally modeled as continuous geometry which at low fidelity converts to discrete representations which behave differently depending on interaction and observation to conserve resources.
We're well on track for knowing quite a lot more about the nature of our reality, and just because things seem uncertain or debatable today doesn't mean they will remain that way into tomorrow.
In fact, looking at much of history, it stands to reason many things we think unknowable will in fact be known in the future.
As to whether we like the eventual answers to the questions we ask is a different topic entirely.