So, while I see the "statistically" part, asking everyone to get zero screenings until you start coughing up blood (or whatever happens when the cancer starts showing very obvious signs)... it just seems weird on the individual level. Nobody knows (nor can they know) if you're the person who would be cured with treatment, or if you're the person whose outcome wouldn't have changed a bit with treatment (for better or for worse). That question matters individually, and while "statistically you're slightly more likely to be in the second group" according to these studies, that doesn't make me feel great about just declining all screenings.