Based on the docs https://manual.os-js.org/, they clearly have some serious intention.
This is what happens when the Wozniak's of the World don't have a Steve to guide them. They do what they want without a clear vision to practicality.
Yes, surely this is proof that every talented coder is only useful when serving a preening egomaniac. I mean, who else is gonna handle all the hard work of getting publicity and taking credit for things?
If their goal includes "practicality", then sure, maybe this indicates that they need a guiding hand.
But, as far as I can tell with all these types of projects, the goal isn't practicality, so you cannot tell whether or not they need a guiding hand.
As far as I can tell, these projects all appear to have made progress towards their goal.
In summary, what you think their goal is, is not what their goal is.
You can then use it to get a job.
You can build a new framework and use that as your portfolio. JS apps like these can be quickly tried in the browser. That's not true of a new Go/Rust/Java library.
JavaScript / Typescript will probably always have a size advantage over WASM anyway because they don't have to ship any runtimes or standard library code. E.g. formatting a string or running a regex in JS is just a few bytes but in Rust you have to ship a whole string formatting/regex library.
Apart from some big companies, no one seem to use it.
No compiler.
No strong types.
No function return types.
And you can combine different types in unexpected ways https://www.destroyallsoftware.com/talks/wat
When the code fails, just refresh the page!