This Reddit thread has a script with a workaround: https://www.reddit.com/r/sysadmin/comments/15ysxgs/applicati...

There are comments saying it's worked on several Quickbooks integrations.

Regarding hardware drivers, I _think_ the same fundamental process of removing signatures should work, but you'll get a UAC prompt to force installation of an unsigned driver.

I'm not as familiar with driver signature enforcement though, so take that with a grain of salt.

P.S: I still have running XP installs for some $300k industrial hardware. It could be worse...