On initial reading, I think This order has a very high chance of increasing the cost of doing business and especially burdening startups. As I read it, the government is asserting the authority to deem any industry as a "critical national resource", and then come in and require that your industry adopt the practices that THEY prescribe to HELP you secure your resources against attack.
This seems to be directed initially at power plants and water supplies. But the stated list of industries includes virtually any business in the US.
I am certain that the largest business and monopolists will make a killing in receiving the benefit of subsidies and reduced competition under this order. But it is just one more barrier that new firms have to hurdle to enter a market.