It's 165 separate problems, of getting (presumably, on average) 1k students to 1 school. That's a much more tractable problem, and if you have a large-scale map and a lot of push-pins, you can probably intuit 90% of the solution.
Yes, the person you're replying to is probably under-estimating the problem, but this isn't a problem you have to rent quantum computing time to solve.
If you have 165 * (1,000 / capacity) busses and drivers, sure.
A good lesson for me, and maybe others, to not confidently offer opinions on areas where we're not even close to being subject matter experts.
(They did this to themselves of course, but suggesting that they just start over with push pins on a large enough scale map ignores why they are in the problem in the first place. The map doesn't make sense. There's no way to intuit a 90% solution because there aren't patterns on the map. They didn't want patterns on the map.)
American schools have been designing bus routes well before they had computers to help them do so. Maybe it requires hiring a few more bus drivers.