Not the same - sites will then take your not opting out of "legitimate interest" as consent. Not valid under GDPR really, but I'm not interested in giving them any argument to stand on.
* You can now also use uBlock Origin to set cookies and LocalStorage entries automatically. The annoyance lists already set opt-out cookies for sites like Google and Youtube
* Firefox has actually been isolating third-party cookies and other site data (e.g. LocalStorage) for over a year. It's pointless for you to ever be concerned about them.