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Comment by tyingq | Hacker News Reader

Also handy is this to run the current buffer through an external command:

  %! somecommand

So, for example, using perl to make everything uppercase:

  %! perl -pe '$_=uc'

I work with python a lot and recently learned you can use this

    %! python

If the buffer you have open is a python script. Doesn’t work great if you have a bunch of stdout to read, but good for quick tests

one of my favorite is

  :%!column -t