Recently I was eating some dried mulberries and I chewed a stone (it was hidden inside a cluster), rendering two of my teeth sensitive and probably damaged my enamel.
Using this for 2.5 months now, and my teeth are neither sensitive, nor I feel that damage anymore. I'll continue a couple of more tubes of this, and It'll be probably completely repaired.
costs billions of dollars. that's the FDA's fault.
And GSK had ~$16 billion in _profit_ last year. It has been profitable for the past 15 years, usually in the $4b range.
They are choosing to not bring this product to market. They are also choosing to not allow another company bring it to market. That is clearly the best business choice for them according to their accounting, but they aren’t limited in trying to do it.
Yeah, because it would cost them too much to get it approved. Which is the FDA's fault.
The FDA should subsidize safety studies for drugs like this. This would actually make it more likely to get useful, functional drugs in the hands of Americans more quickly, ie the whole point of this article.
> And if you don't think drastically reducing the barriers to entry for products in to the us would make us less safe I'm certainly open to hearing how.
Most of the barriers to entry are more bureaucracy than safety, and the net effect is fewer medicines are available and those that are are more expensive. The greatest success story of the FDA is thalidomide, which killed or seriously injured around 100,000 worldwide over 50 years ago; meanwhile about 45,000 americans die every year from not being able to afford medical treatment, and that only accounts for medicines that made it through the approval process, not those where it wasn't economical to try.
Between being early on the applied genetic manipulation tech wave, having a product that reproduces itself and sticks around forever (cue the FDAs concern meter rising) and at least in the eyes of the FDA not really fitting into any existing licensable food/drug categories they have established procedures for… the company stalled … and pivoted to selling some kind of water product I think.
Forget cavities though, brushing is great to get rid of film and grime and stench. I’ll keep brushing.
But Duhigg argues the brand might not have succeeded if it weren’t for Pepsodent’s unique ingredient list. The inventor “had decided to add a little bit of mint extract. Mint extract, as well as a couple of other ingredients that he added, are irritants. They cause our tongues and our gum to tingle.”
And the effect of that tingling? It told people that “the toothpaste was working,” said Duhigg, “even though it had nothing to do with how the toothpaste actually worked. And people began to equate that tingling feeling with good dental hygiene. And as a result they began to crave it.”
https://www.marketplace.org/2018/03/16/mouth-full-mint-clean...
I work in healthcare and I’ve smelled a lot of really not nice things, bad breathe can really really stink. It’s not a cultural thing it’s more like a “good lord, shut your mouth you smell like you have a pile of MRSA infected shit festival in your mouth”
I used to smoke and other things, I have terrible sense of smell except when it comes to festering wounds and/or shit, especially infected shit. I pick those up like a hound dog and I know when someone isn’t brushing pretty quickly.
I do believe that mint thing though, I’ve been experimenting with different flavors ginger and orange cream and etc (non minty) and I miss the minty feed back.
I am now fully convinced that the dentist lobby is keeping the caries vaccine from us.
Many, many dentists do this now, all it takes is the willingness to lie.