As for events, binding is really very easy to do and it's already localised to the component so managing them is trivial.
Loops are also trivial; you can simply use Array.prototype.map function to return a bunch of strings which you can incorporate directly into the main component's template string. In any case, you can always use the native document.createElement and appendChild functions to create elements within the component and add them to its DOM or shadow DOM.
I've built some complex apps with plain HTMLElement as a base class for all my components and found is much simpler than React without any unexpected weirdness and using fewer abstract technical concepts. Code was much more readable and maintainable. I didn't even need a bundler thanks to modern async and defer attributes of script tags among others.
I think the reason why people are using React still is just marketing, hype and inertia. The job market which is gatekept by non-technical recruiters demands React. It's all non-tech people making the big decisions based on buzzwords that they don't understand.