My primary issue with it is the lack of support for in app purchases (last checked in late 2022).
The only easy way to do it is via RevenueCat, as none of the other RN IAP libraries work with Expo.
Expo also has built in support for over-the-air updates, which is great. However, it is a paid product, for $5/m per 1000 users (first 1000 free).
I believe you can run your own server for OTA updates, but it's fairly obvious that this feature will eventually be removed when they need to monetize harder.