Adult family relationships have historically been culturally mandatory and unseverable but that’s increasingly not the case in the US.
Cultural messages that use therapy-speak, if not necessarily promulgated by actual therapists, encourages more and more atomization. Anyone that is annoying, disagreeable, or who has the wrong ideology is labeled “toxic” and people are encouraged to cut them out of their lives. This includes parents, siblings, spouses—of course an uncle or cousin is entirely disposable.