Just out of curiosity, do you mean the person's self-confidence may dramatically improve with use? The only reason is because I had a recent co-worker who was laid off after taking psychedelics for a decent period of time. He effectively stopped contributing to the team and started making concerted efforts to get the CEO to establish a new, special position for him so that "real work" could get done and the "company would function 100x better."
Seeing the before and after was fairly dramatic. I tried to encourage them to stop using, but that "self-confidence" was so over the top that they ignored all of us and eventually lost their job.